righto so you can only have 1 of each type of ammy and obviously you can only get 4 ammys. So on my Tanky tank swishinator i use the mastery ammy(the book), attack speed one(wolfy head), health buff one(basilisk heart) and health regen (the onk thingy)
with all of those my character has OP life (13k when fully equipped) has good attack speed so you can beat most zerkers easily and with the mastery buff too can still deal a decent amount of damage
but some tank's do go other ways as i know some who don't focus on HP at all and just go for loads of damage output with mastery but i don't really believe that's the correct way as your main role is to tank damage and survive in all circumstances and not to deal huge damage...that's a zerkers role
hope this helps